Sodium Stearyl Fumarate (SSF) Pharmaceutical Lubricant | Kuenderana Kwakawanda kweAPI, Imwe Nzira yeMagnesium Stearate, GMP Giredhi

Sodium Stearyl Fumarate (SSF) yedu imafuta emushonga akachena kwazvo akagadzirirwa mapiritsi nemakapisi. Kusiyana nemagnesium stearate, ine API inoenderana zvakanaka, yakasimba kana ichizorwa zvakanyanya, uye haina mhedzisiro yakaipa pakushandiswa kwemafuta mumuviri.. Imafuta anonyungudika mumvura, anonyungudika zvishoma nezvishoma anopa kuomarara kwakanyanya kwepiritsi padanho rakaenzana rekudzvanya uye anoderedza kukanganisa kwenguva yekuputsika.. Inoenderana neUSP-NF, EP, uye JP pharmacopoeias ine CDE registration (F20190000009) uye rutsigiro rweDMF (38822). Hunhu hunokurudzirwa hwekushandisa: 0.5-3% w/wYakanakira kudzvanywa kwakananga nekukurumidza, mapiritsi anopenya, uye mafomura ane maAPI asingaenderane.

Taura nesu

Ruzivo rweChigadzirwa

Mishonga yeGiredhi reSodium Stearyl Fumarate (SSF)

Pfupiso yeChigadzirwa

Sodium Stearyl Fumarate (SSF) imafuta emushonga anoshanda zvakanyanya anozivikanwa zvakanyanya senzira yepamusoro pane mafuta echinyakare akadai semagnesium stearate netalc.Isodium munyu we stearyl fumaric acid, inoonekwa seupfu hwakatsetseka huchena kusvika kuchena hune hunhu hwe amphiphilic hunoita kuti mafuta ashande zvakanaka mumafomu emapiritsi nema capsule..

Kuzivikanwa Kwechigadzirwa:

Zita reKemikari:Sodium Stearyl Fumarate
Nhamba yeCAS:4070-80-8
Nhamba yekunyoresa yeCDE:F20190000009
Nhamba yeDMF:38822
Kutevedzera Mutemo wePharmacopoeia:USP-NF, EP, JP
Fomura reMamorekuru:C22H39NaO4
Kurema kweMorekuru:390.53 g/mol

Zvinhu Zvikuru & Mabhenefiti

1. Kuenderana kweSuperior API

Inogadzirisa matambudziko ekubatana anowanzo sangana ne magnesium stearate
Zvakataurwa kuti kusawirirana kweAPI nemagnesium stearate zvinosanganisira: Azathioprine, Cefaclor, Cilazapril, Clopidogrel, Diclofenac, Ibuprofen, Omeprazole, nezvimwe zvakawanda.
Yakanakira mafomura apo kusawirirana kwemakemikari kuri dambudziko

2. Kusimba kusvika pakuzora mafuta zvakanyanya

Kusiyana nemagnesium stearate, SSF inochengetedza mashandiro kunyangwe paine nguva yakareba yekusanganisa
Inopa kuomarara kwepiritsi uye kuparara kwaro nguva dzose pasina "kunyanya kunyorovesa"

3. Hunhu Hwakagadziridzwa hweTablet

Kuoma kwakanyanyapamasimba ekumanikidza akaenzana kana tichienzanisa nemamwe mafuta ekuzora
Kukanganisa kushoma panguva yekuputsika- inochengetedza kukuvara kwepiritsi nekukurumidza
Hapana mhedzisiro yakaipa pakushandiswa kwe bioavailability- inoita kuti ma profiles ekuburitswa kwemishonga arambe aripo

4. Hunhu Hwemvura Hunonyungudika Uye Hunonyungudika Zvishoma

Mafuta anonyungudika mumvura – 0.5 mg/100 mL pa25°C, zvichiwedzera kusvika 20 g/100 mL pa90°C
Zvinoguma nekushomeka kwemvura mumushonga, zvichiita kuti ive yakanaka kunemapiritsi anodzima moto
Inovandudza ma profiles ekunyungudika kwemaAPI asina kunyungudika zvakanaka

5. Hunhu Hwakanaka Hwemuviri